| 5. Jornada | 04.09.2010 | Tranmere Rovers | - | Peterborough United | 1:0 |  |
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| 6. Jornada | 11.09.2010 | Yeovil Town | - | Tranmere Rovers | 3:1 | |
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| 7. Jornada | 18.09.2010 | Tranmere Rovers | - | Charlton Athletic | 1:1 | ||||
| 8. Jornada | 25.09.2010 | Colchester United | - | Tranmere Rovers | 3:1 | |
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| 9. Jornada | 28.09.2010 | Bristol Rovers | - | Tranmere Rovers | 0:1 | ||||
| 10. Jornada | 02.10.2010 | Tranmere Rovers | - | Brighton & Hove Albion | 1:1 | ||||
| 11. Jornada | 09.10.2010 | Southampton | - | Tranmere Rovers | 2:0 | ||||
| 12. Jornada | 16.10.2010 | Tranmere Rovers | - | Brentford FC | 0:3 | ||||
| 13. Jornada | 23.10.2010 | Walsall FC | - | Tranmere Rovers | 1:4 | ||||
| 16. Jornada | 13.11.2010 | Tranmere Rovers | - | Plymouth Argyle | 1:0 | |
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| 17. Jornada | 20.11.2010 | Notts County | - | Tranmere Rovers | 0:1 | ||||
| 18. Jornada | 23.11.2010 | Tranmere Rovers | - | Hartlepool United | 0:1 | |
Francia