| 1. Jornada | 08.08.2021 | Girondins de Burdeos | - | Clermont Foot 63 | 0:2 | ||||
| 2. Jornada | 15.08.2021 | Clermont Foot 63 | - | Troyes | 2:0 | ||||
| 3. Jornada | 22.08.2021 | Lyon | - | Clermont Foot 63 | 3:3 | ||||
| 4. Jornada | 29.08.2021 | Clermont Foot 63 | - | FC Metz | 2:2 | ||||
| 5. Jornada | 11.09.2021 | París Saint-Germain | - | Clermont Foot 63 | 4:0 | ||||
| 6. Jornada | 19.09.2021 | Clermont Foot 63 | - | Stade Brestois 29 | 1:1 | ||||
| 7. Jornada | 22.09.2021 | Rennes | - | Clermont Foot 63 | 6:0 | ||||
| 8. Jornada | 26.09.2021 | Clermont Foot 63 | - | Mónaco | 1:3 | ||||
| 9. Jornada | 03.10.2021 | Lorient | - | Clermont Foot 63 | 1:1 | ||||
| 10. Jornada | 16.10.2021 | Clermont Foot 63 | - | Lille | 1:0 | ||||
| 11. Jornada | 23.10.2021 | Nantes | - | Clermont Foot 63 | 2:1 | ||||
| 12. Jornada | 31.10.2021 | Clermont Foot 63 | - | Marsella | 0:1 | ||||
| 13. Jornada | 07.11.2021 | Saint-Étienne | - | Clermont Foot 63 | 3:2 | ||||
| 31. Jornada | 09.04.2022 | Clermont Foot 63 | - | París Saint-Germain | 1:6 | ||||
| 32. Jornada | 17.04.2022 | FC Metz | - | Clermont Foot 63 | 1:1 |
Francia