| 5. Jornada | 28.07.2022 | Pumas UNAM | - | Mazatlán FC | 1:1 | ||||
| 6. Jornada | 31.07.2022 | Pumas UNAM | - | CF Monterrey | 1:1 | ||||
| 8. Jornada | 14.08.2022 | Pumas UNAM | - | CF América | 0:3 | ||||
| 12. Jornada | 04.09.2022 | Atlas Guadalajara | - | Pumas UNAM | 0:0 |  |
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| 13. Jornada | 08.09.2022 | Pumas UNAM | - | Gallos Blancos | 4:1 | ||||
| 14. Jornada | 11.09.2022 | Deportivo Toluca | - | Pumas UNAM | 2:2 | |
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| 15. Jornada | 19.09.2022 | Pumas UNAM | - | Cruz Azul | 1:2 | ||||
| 7. Jornada | 24.09.2022 | Puebla FC | - | Pumas UNAM | 2:1 | |
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| 17. Jornada | 01.10.2022 | FC Juárez | - | Pumas UNAM | 3:1 |
México