| 3. Jornada | 25.04.2021 | Deportes Iquique | - | San Marcos | 1:2 | ||||
| 9. Jornada | 06.06.2021 | Deportes Iquique | - | Universidad de Concepción | 5:1 | ||||
| 10. Jornada | 09.07.2021 | Cobreloa | - | Deportes Iquique | 3:2 | ||||
| 11. Jornada | 15.07.2021 | Unión San Felipe | - | Deportes Iquique | 3:1 | ||||
| 12. Jornada | 24.07.2021 | Deportes Iquique | - | Santiago Morning | 1:2 |  |
|||
| 2. Jornada | 30.07.2021 | Fernández Vial | - | Deportes Iquique | 0:1 | ||||
| 15. Jornada | 15.08.2021 | Puerto Montt | - | Deportes Iquique | 0:0 | ||||
| 18. Jornada | 02.09.2021 | San Marcos | - | Deportes Iquique | 4:2 | |
|||
| 20. Jornada | 16.09.2021 | San Luis | - | Deportes Iquique | 1:1 | ||||
| 21. Jornada | 23.09.2021 | Deportes Iquique | - | Deportes Copiapó | 2:1 | ||||
| 22. Jornada | 27.09.2021 | CD Magallanes | - | Deportes Iquique | 2:2 | ||||
| 26. Jornada | 20.10.2021 | Deportes Iquique | - | Unión San Felipe | 1:0 |
Chile