| 1. Jornada | 11.01.2020 | Club Tijuana | - | Santos Laguna | 2:1 |  |
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| 2. Jornada | 20.01.2020 | Santos Laguna | - | Club León | 3:2 |  |
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| 3. Jornada | 26.01.2020 | Cruz Azul | - | Santos Laguna | 3:0 | ||||
| 4. Jornada | 02.02.2020 | Santos Laguna | - | Pumas UNAM | 1:1 | |
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| 5. Jornada | 08.02.2020 | Puebla FC | - | Santos Laguna | 2:2 | ||||
| 6. Jornada | 17.02.2020 | Santos Laguna | - | UANL Tigres | 2:1 | ||||
| 7. Jornada | 24.02.2020 | FC Juárez | - | Santos Laguna | 1:2 | |
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| 8. Jornada | 02.03.2020 | Santos Laguna | - | Atlas Guadalajara | 1:0 | ||||
| 9. Jornada | 08.03.2020 | CF Pachuca | - | Santos Laguna | 1:0 | |
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| 10. Jornada | 16.03.2020 | Santos Laguna | - | Club Necaxa | 2:1 | |
Uruguay
