| 1. Jornada | 19.02.2022 | Emelec | - | Macará | 4:0 | ||||
| 2. Jornada | 28.02.2022 | Independiente del Valle | - | Emelec | 0:1 | ||||
| 3. Jornada | 05.03.2022 | Emelec | - | Guayaquil City | 2:2 | ||||
| 4. Jornada | 14.03.2022 | Gualaceo SC | - | Emelec | 2:1 | ||||
| 5. Jornada | 21.03.2022 | Emelec | - | Delfín SC | 1:2 |  |
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| 7. Jornada | 10.04.2022 | Deportivo Cuenca | - | Emelec | 2:2 | ||||
| 10. Jornada | 25.04.2022 | Emelec | - | Aucas | 1:0 | ||||
| 12. Jornada | 08.05.2022 | Emelec | - | Mushuc Runa | 4:0 |
Argentina