| 2. Jornada | 02.07.2022 | CF Monterrey [] | - | Mazatlán FC [] | 4:1 | ||||
| 3. Jornada | 09.07.2022 | Mazatlán FC [] | - | Atlético San Luis [] | 1:2 | ||||
| 5. Jornada | 23.07.2022 | Santos Laguna [] | - | Mazatlán FC [] | 5:0 | ||||
| 6. Jornada | 30.07.2022 | Mazatlán FC [] | - | Atlas Guadalajara [] | 2:5 | ||||
| 7. Jornada | 06.08.2022 | UANL Tigres [] | - | Mazatlán FC [] | 2:1 | ||||
| 8. Jornada | 13.08.2022 | Mazatlán FC [] | - | Club León [] | 3:0 | ||||
| 9. Jornada | 20.08.2022 | Deportivo Guadalajara [] | - | Mazatlán FC [] | 4:1 | ||||
| 13. Jornada | 17.09.2022 | Mazatlán FC [] | - | UANL Tigres [] | 0:3 | ||||
| 14. Jornada | 24.09.2022 | Atlas Guadalajara [] | - | Mazatlán FC [] | 3:1 |  |
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| 15. Jornada | 01.10.2022 | Mazatlán FC [] | - | Santos Laguna [] | 2:3 | ||||
| 17. Jornada | 15.10.2022 | Atlético San Luis [] | - | Mazatlán FC [] | 2:2 | |
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| 18. Jornada | 22.10.2022 | Mazatlán FC [] | - | CF Monterrey [] | 0:4 |
Estados Unidos
México