| 2. Jornada | 09.07.2022 | Cruz Azul [Sub 20] | - | CF Pachuca [Sub 20] | 0:2 | ||||
| 3. Jornada | 16.07.2022 | Atlas Guadalajara [Sub 20] | - | Cruz Azul [Sub 20] | 2:0 |  |
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| 7. Jornada | 06.08.2022 | Santos Laguna [Sub 20] | - | Cruz Azul [Sub 20] | 2:1 | ||||
| 8. Jornada | 13.08.2022 | Cruz Azul [Sub 20] | - | Deportivo Toluca [Sub 20] | 1:0 | ||||
| 9. Jornada | 17.08.2022 | Cruz Azul [Sub 20] | - | Club Tijuana [Sub 20] | 0:1 | ||||
| 10. Jornada | 20.08.2022 | CF América [Sub 20] | - | Cruz Azul [Sub 20] | 2:0 | ||||
| 11. Jornada | 27.08.2022 | Cruz Azul [Sub 20] | - | Gallos Blancos [Sub 20] | 3:1 | ||||
| 13. Jornada | 06.09.2022 | CF Monterrey [Sub 20] | - | Cruz Azul [Sub 20] | 4:2 | ||||
| 14. Jornada | 11.09.2022 | Cruz Azul [Sub 20] | - | Mazatlán FC [Sub 20] | 1:2 |  |
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| 16. Jornada | 15.09.2022 | Cruz Azul [Sub 20] | - | Club León [Sub 20] | 1:1 | ||||
| 15. Jornada | 18.09.2022 | Pumas UNAM [Sub 20] | - | Cruz Azul [Sub 20] | 2:0 |
México