| 1. Jornada | 15.01.2022 | Sporting Canamy | - | Lobos ULMX | 2:2 |  |
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| 2. Jornada | 23.01.2022 | Lobos ULMX | - | Yalmakan FC | 0:1 | ||||
| 3. Jornada | 30.01.2022 | Lobos ULMX | - | Inter Playa | 1:4 | ||||
| 4. Jornada | 07.02.2022 | Reboceros de La Piedad | - | Lobos ULMX | 1:2 | ||||
| 5. Jornada | 13.02.2022 | Lobos ULMX | - | Deportivo Dongu | 2:0 | ||||
| 6. Jornada | 19.02.2022 | Cañoneros FC | - | Lobos ULMX | 0:1 | ||||
| 8. Jornada | 05.03.2022 | Escorpiones | - | Lobos ULMX | 0:1 | ||||
| 9. Jornada | 13.03.2022 | Lobos ULMX | - | Cafetaleros de Chiapas | 0:0 | ||||
| 10. Jornada | 18.03.2022 | CD Zap | - | Lobos ULMX | 3:1 | ||||
| 11. Jornada | 27.03.2022 | Lobos ULMX | - | Inter de Querétaro | 0:0 | ||||
| 12. Jornada | 04.04.2022 | Montañeses FC | - | Lobos ULMX | 1:0 | ||||
| 13. Jornada | 10.04.2022 | Lobos ULMX | - | Leviatán FC | 1:0 |
México