| 1. Jornada | 24.07.2010 | La Paz FC | - | Real Potosí | 1:2 |  |
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| 2. Jornada | 31.07.2010 | Universitario de Sucre | - | La Paz FC | 3:1 | |
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| 3. Jornada | 08.08.2010 | La Paz FC | - | Oriente Petrolero | 0:0 | |
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| 4. Jornada | 15.08.2010 | Blooming | - | La Paz FC | 2:0 | |
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| 5. Jornada | 22.08.2010 | La Paz FC | - | Club Aurora | 1:1 |  |
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| 6. Jornada | 29.08.2010 | Jorge Wilstermann | - | La Paz FC | 4:2 | |
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| 8. Jornada | 09.09.2010 | The Strongest | - | La Paz FC | 1:3 | |
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| 9. Jornada | 12.09.2010 | La Paz FC | - | Real Mamoré | 1:0 | |
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| 10. Jornada | 19.09.2010 | CD Guabirá | - | La Paz FC | 1:0 | |
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| 11. Jornada | 25.09.2010 | La Paz FC | - | Club San José | 4:3 | |
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| 12. Jornada | 02.10.2010 | Real Potosí | - | La Paz FC | 2:3 | |
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| 14. Jornada | 11.10.2010 | Oriente Petrolero | - | La Paz FC | 1:0 | |
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| 15. Jornada | 17.10.2010 | La Paz FC | - | Blooming | 4:1 | ||||
| 13. Jornada | 27.10.2010 | La Paz FC | - | Universitario de Sucre | 1:1 | |
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| 18. Jornada | 31.10.2010 | Bolívar | - | La Paz FC | 4:4 | |
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| 19. Jornada | 07.11.2010 | La Paz FC | - | The Strongest | 0:1 | ||||
| 21. Jornada | 21.11.2010 | La Paz FC | - | CD Guabirá | 3:1 |
Bolivia