| 1. Jornada | 20.08.2017 | Rampla Juniors | - | Defensor Sporting | 2:2 | ||||
| 8. Jornada | 05.11.2017 | Peñarol | - | Defensor Sporting | 3:1 |  |
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| 10. Jornada | 12.11.2017 | El Tanque Sisley | - | Defensor Sporting | 0:2 | ||||
| 12. Jornada | 19.11.2017 | Boston River | - | Defensor Sporting | 0:1 | ||||
| 13. Jornada | 23.11.2017 | Defensor Sporting | - | Montevideo Wanderers | 2:1 | ||||
| 14. Jornada | 26.11.2017 | Nacional | - | Defensor Sporting | 1:1 | ||||
| 15. Jornada | 03.12.2017 | Defensor Sporting | - | Fénix | 0:2 |
Panamá