| 3. Jornada | 29.01.2023 | Olimpia | - | Marathón | 0:0 | ||||
| 4. Jornada | 03.02.2023 | Marathón | - | Real España | 2:1 |  |
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| 5. Jornada | 05.02.2023 | Marathón | - | Victoria | 1:0 | ||||
| 6. Jornada | 12.02.2023 | Lobos UPNFM | - | Marathón | 2:1 | ||||
| 7. Jornada | 16.02.2023 | Marathón | - | Honduras Progreso | 1:0 | ||||
| 8. Jornada | 19.02.2023 | Marathón | - | Motagua | 1:1 | ||||
| 9. Jornada | 26.02.2023 | Real Sociedad | - | Marathón | 1:1 | ||||
| 10. Jornada | 01.03.2023 | Marathón | - | Olancho FC | 0:2 | ||||
| 11. Jornada | 05.03.2023 | Vida | - | Marathón | 0:0 | ||||
| 12. Jornada | 12.03.2023 | Marathón | - | Olimpia | 2:0 | ||||
| 13. Jornada | 20.03.2023 | Real España | - | Marathón | 0:1 | ||||
| 14. Jornada | 02.04.2023 | Victoria | - | Marathón | 0:1 | ||||
| 15. Jornada | 06.04.2023 | Marathón | - | Lobos UPNFM | 1:1 | ||||
| 16. Jornada | 15.04.2023 | Honduras Progreso | - | Marathón | 2:1 | ||||
| 17. Jornada | 24.04.2023 | Motagua | - | Marathón | 2:2 | ||||
| 18. Jornada | 29.04.2023 | Marathón | - | Real Sociedad | 1:0 |
Panamá