| 20. Jornada | 07.12.2021 | Oldham Athletic | - | Tranmere Rovers | 0:1 |  |
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| 21. Jornada | 11.12.2021 | Exeter City | - | Tranmere Rovers | 0:1 |  |
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| 22. Jornada | 18.12.2021 | Tranmere Rovers | - | Leyton Orient | 1:0 | ||||
| 26. Jornada | 08.01.2022 | Tranmere Rovers | - | Scunthorpe United | 4:0 | |
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| 25. Jornada | 11.01.2022 | Salford City | - | Tranmere Rovers | 1:1 | ||||
| 27. Jornada | 15.01.2022 | Tranmere Rovers | - | Rochdale AFC | 2:0 | |
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| 28. Jornada | 22.01.2022 | Crawley Town | - | Tranmere Rovers | 0:1 | ||||
| 29. Jornada | 29.01.2022 | Tranmere Rovers | - | Forest Green Rovers | 0:4 | ||||
| 31. Jornada | 08.02.2022 | Tranmere Rovers | - | Swindon Town | 3:0 | ||||
| 32. Jornada | 12.02.2022 | Walsall FC | - | Tranmere Rovers | 1:0 | ||||
| 24. Jornada | 15.02.2022 | Hartlepool United | - | Tranmere Rovers | 1:0 | ||||
| 39. Jornada | 26.03.2022 | Colchester United | - | Tranmere Rovers | 1:0 | |
Inglaterra