| 1. Jornada | 07.08.2021 | Tranmere Rovers | - | Walsall FC | 1:0 |  |
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| 5. Jornada | 28.08.2021 | Scunthorpe United | - | Tranmere Rovers | 1:0 |  |
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| 10. Jornada | 02.10.2021 | Tranmere Rovers | - | Crawley Town | 2:1 | |
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| 11. Jornada | 08.10.2021 | Tranmere Rovers | - | Colchester United | 2:0 | ||||
| 21. Jornada | 11.12.2021 | Exeter City | - | Tranmere Rovers | 0:1 | ||||
| 22. Jornada | 18.12.2021 | Tranmere Rovers | - | Leyton Orient | 1:0 | ||||
| 23. Jornada | 26.12.2021 | Tranmere Rovers | - | Barrow AFC | 2:0 | ||||
| 28. Jornada | 22.01.2022 | Crawley Town | - | Tranmere Rovers | 0:1 | ||||
| 19. Jornada | 01.02.2022 | Tranmere Rovers | - | Stevenage FC | 1:0 | ||||
| 39. Jornada | 26.03.2022 | Colchester United | - | Tranmere Rovers | 1:0 | ||||
| 40. Jornada | 02.04.2022 | Tranmere Rovers | - | Carlisle United | 2:2 | ||||
| 41. Jornada | 09.04.2022 | Tranmere Rovers | - | Bristol Rovers | 1:1 | |
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| 42. Jornada | 15.04.2022 | Bradford City | - | Tranmere Rovers | 1:1 | ||||
| 43. Jornada | 18.04.2022 | Tranmere Rovers | - | Exeter City | 2:0 | ||||
| 44. Jornada | 23.04.2022 | Stevenage FC | - | Tranmere Rovers | 2:0 |
Inglaterra