| 3. Jornada | 22.01.2022 | Atlas Guadalajara [] | - | CF Monterrey [] | 2:1 | ||||
| 4. Jornada | 29.01.2022 | CF Monterrey [] | - | Mazatlán FC [] | 3:2 | ||||
| 7. Jornada | 19.02.2022 | Club Tijuana [] | - | CF Monterrey [] | 1:1 | ||||
| 10. Jornada | 12.03.2022 | Mazatlán FC [] | - | CF Monterrey [] | 1:3 | ||||
| 13. Jornada | 03.04.2022 | CF Monterrey [] | - | Santos Laguna [] | 2:0 |
México