| 1. Jornada | 17.04.2021 | Houston Dynamo | - | San Jose Earthquakes | 2:1 | ||||
| 1. Jornada | 25.04.2021 | Portland Timbers | - | Houston Dynamo | 2:1 | ||||
| 2. Jornada | 01.05.2021 | Houston Dynamo | - | Los Angeles FC | 1:1 | ||||
| 2. Jornada | 13.05.2021 | Houston Dynamo | - | Sporting Kansas City | 1:0 | ||||
| 2. Jornada | 16.05.2021 | Colorado Rapids | - | Houston Dynamo | 3:1 |  |
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| 2. Jornada | 23.05.2021 | Houston Dynamo | - | Vancouver Whitecaps | 2:1 |
Estados Unidos
Colombia