| 1. Jornada | 13.01.2022 | Municipal Pérez Zeledón | - | Municipal Grecia | 1:1 | ||||
| 2. Jornada | 16.01.2022 | CS Cartaginés | - | Municipal Pérez Zeledón | 2:1 | ||||
| 3. Jornada | 22.01.2022 | AD San Carlos | - | Municipal Pérez Zeledón | 1:1 | ||||
| 10. Jornada | 08.03.2022 | Municipal Pérez Zeledón | - | Jicaral | 2:1 | ||||
| 11. Jornada | 01.04.2022 | CS Herediano | - | Municipal Pérez Zeledón | 3:2 | ||||
| 18. Jornada | 02.05.2022 | Deportivo Saprissa | - | Municipal Pérez Zeledón | 2:1 | ||||
| 19. Jornada | 05.05.2022 | Municipal Pérez Zeledón | - | Sporting FC | 0:1 | ||||
| 20. Jornada | 08.05.2022 | Guadalupe | - | Municipal Pérez Zeledón | 2:2 | ||||
| 21. Jornada | 11.05.2022 | Jicaral | - | Municipal Pérez Zeledón | 2:1 | ||||
| 22. Jornada | 15.05.2022 | Municipal Pérez Zeledón | - | CS Herediano | 2:3 |  |
Costa Rica