| 9. Jornada | 24.02.2022 | Cancún FC | - | CF Monterrey II | 0:0 | ||||
| 10. Jornada | 03.03.2022 | CF Monterrey II | - | Venados FC | 3:3 | ||||
| 11. Jornada | 09.03.2022 | TM Fútbol Club | - | CF Monterrey II | 0:0 | ||||
| 13. Jornada | 24.03.2022 | Leones Negros | - | CF Monterrey II | 0:0 | ||||
| 16. Jornada | 08.04.2022 | CF Monterrey II | - | Tepatitlán | 0:2 | ||||
| 12. Jornada | 10.04.2022 | CF Monterrey II | - | Dorados de Sinaloa | 0:1 | ||||
| 17. Jornada | 16.04.2022 | Tapatío | - | CF Monterrey II | 1:2 |
México