| 6. Jornada | 28.02.2010 | Club Olimpia | - | Cerro Porteño | 3:2 |  |
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| 7. Jornada | 07.03.2010 | Sport Colombia | - | Club Olimpia | 0:4 | ||||
| 8. Jornada | 12.03.2010 | Club Olimpia | - | 3 de Febrero | 1:0 | ||||
| 9. Jornada | 16.03.2010 | Sol de América | - | Club Olimpia | 2:1 | ||||
| 10. Jornada | 20.03.2010 | Libertad | - | Club Olimpia | 0:0 | ||||
| 11. Jornada | 28.03.2010 | Club Olimpia | - | Guaraní | 0:0 | |
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| 13. Jornada | 10.04.2010 | Tacuary | - | Club Olimpia | 0:4 | ||||
| 14. Jornada | 16.04.2010 | Club Olimpia | - | Sportivo Luqueño | 2:1 | ||||
| 17. Jornada | 02.05.2010 | Cerro Porteño | - | Club Olimpia | 0:0 | ||||
| 18. Jornada | 09.05.2010 | Club Olimpia | - | Sport Colombia | 2:1 |
Paraguay