| 3. Jornada | 27.02.2021 | Talleres de Córdoba | - | Newell's Old Boys | 2:2 |  |
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| 4. Jornada | 05.03.2021 | Newell's Old Boys | - | Independiente | 1:2 | ||||
| 5. Jornada | 13.03.2021 | Defensa y Justicia | - | Newell's Old Boys | 4:0 | |
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| 6. Jornada | 19.03.2021 | Newell's Old Boys | - | Unión de Santa Fe | 0:0 | ||||
| 7. Jornada | 30.03.2021 | Atlético Tucumán | - | Newell's Old Boys | 2:2 |  |
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| 8. Jornada | 04.04.2021 | Newell's Old Boys | - | Huracán | 2:2 | ||||
| 9. Jornada | 13.04.2021 | CA Lanús | - | Newell's Old Boys | 1:3 | ||||
| 10. Jornada | 18.04.2021 | Newell's Old Boys | - | Patronato de Paraná | 2:0 | ||||
| 11. Jornada | 26.04.2021 | Gimnasia de La Plata | - | Newell's Old Boys | 2:1 | ||||
| 12. Jornada | 03.05.2021 | Rosario Central | - | Newell's Old Boys | 3:0 | |
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| 13. Jornada | 10.05.2021 | Newell's Old Boys | - | Sarmiento de Junín | 1:1 | |
Argentina
