| 1. Jornada | 16.07.2021 | Huracán II | - | Defensa y Justicia II | 3:0 |  |
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| 3. Jornada | 27.07.2021 | Huracán II | - | Colón de Santa Fe II | 0:1 | ||||
| 4. Jornada | 30.07.2021 | River Plate II | - | Huracán II | 2:0 | ||||
| 5. Jornada | 06.08.2021 | Huracán II | - | Lanús II | 0:2 | ||||
| 8. Jornada | 25.08.2021 | Huracán II | - | Vélez Sarsfield II | 2:2 | ||||
| 9. Jornada | 30.08.2021 | Gimnasia de La Plata II | - | Huracán II | 2:0 | ||||
| 10. Jornada | 03.09.2021 | Huracán II | - | Aldosivi II | 2:1 | ||||
| 12. Jornada | 17.09.2021 | Huracán II | - | Independiente II | 2:0 | ||||
| 13. Jornada | 24.09.2021 | Newell's Old Boys II | - | Huracán II | 2:0 | ||||
| 14. Jornada | 30.09.2021 | Huracán II | - | Arsenal de Sarandí II | 1:0 | ||||
| 15. Jornada | 08.10.2021 | Central Córdoba SdE II | - | Huracán II | 2:1 | ||||
| 16. Jornada | 13.10.2021 | Huracán II | - | Boca Juniors II | 1:2 | ||||
| 17. Jornada | 18.10.2021 | Banfield II | - | Huracán II | 1:2 | ||||
| 18. Jornada | 22.10.2021 | Huracán II | - | San Lorenzo II | 0:1 | ||||
| 19. Jornada | 31.10.2021 | Talleres de Córdoba II | - | Huracán II | 0:0 | ||||
| 22. Jornada | 23.11.2021 | Huracán II | - | Patronato de Paraná II | 1:0 |
Paraguay