| 1. Jornada | 18.09.2021 | Lobos Huerta | - | Club Calor | 2:1 |  |
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| 2. Jornada | 25.09.2021 | Club Calor | - | CD Cuautla | 1:1 | ||||
| 3. Jornada | 02.10.2021 | Club de Ciervos | - | Club Calor | 0:3 | |
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| 4. Jornada | 09.10.2021 | Club Calor | - | Alebrijes de Oaxaca II | 1:2 | |
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| 5. Jornada | 14.10.2021 | Club Calor | - | Huracanes Izcalli | 4:1 | ||||
| 6. Jornada | 16.10.2021 | Aguacateros CDU | - | Club Calor | 3:2 | ||||
| 7. Jornada | 23.10.2021 | Club Calor | - | Guerreros Xico | 2:0 | ||||
| 8. Jornada | 30.10.2021 | Club Calor | - | Lobos Huerta | 5:0 |  |
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| 9. Jornada | 07.11.2021 | CD Cuautla | - | Club Calor | 2:1 | ||||
| 10. Jornada | 11.11.2021 | Club Calor | - | Club de Ciervos | 4:0 | ||||
| 11. Jornada | 15.11.2021 | Alebrijes de Oaxaca II | - | Club Calor | 2:1 | ||||
| 14. Jornada | 04.12.2021 | Guerreros Xico | - | Club Calor | 1:4 |
México