| 1. Jornada | 21.09.2020 | Hamrun Spartans | - | Sirens FC | 5:1 | ||||
| 2. Jornada | 25.09.2020 | Sirens FC | - | Sliema Wanderers | 0:0 | ||||
| 3. Jornada | 01.10.2020 | Floriana FC | - | Sirens FC | 3:2 | ||||
| 4. Jornada | 07.11.2020 | Sirens FC | - | Tarxien Rainbows | 2:2 | ||||
| 7. Jornada | 15.11.2020 | Lija Athletics FC | - | Sirens FC | 0:2 | ||||
| 8. Jornada | 20.11.2020 | Sirens FC | - | Zejtun Corinthians | 0:4 | ||||
| 14. Jornada | 05.01.2021 | Sirens FC | - | Birkirkara FC | 2:4 | ||||
| 15. Jornada | 09.01.2021 | Balzan FC | - | Sirens FC | 1:0 | ||||
| 13. Jornada | 12.01.2021 | Senglea Athletics | - | Sirens FC | 0:1 | ||||
| 16. Jornada | 15.01.2021 | Sirens FC | - | Hamrun Spartans | 0:1 | ||||
| 17. Jornada | 23.01.2021 | Sliema Wanderers | - | Sirens FC | 1:3 | ||||
| 20. Jornada | 14.02.2021 | Sirens FC | - | Valletta FC | 0:1 | ||||
| 21. Jornada | 21.02.2021 | Mosta FC | - | Sirens FC | 0:0 | ||||
| 22. Jornada | 26.02.2021 | Sirens FC | - | Lija Athletics FC | 1:1 | ||||
| 23. Jornada | 07.03.2021 | Zejtun Corinthians | - | Sirens FC | 1:1 |
Malta