| 1. Jornada | 07.08.2010 | Southampton | - | Plymouth Argyle | 0:1 | ||||
| 3. Jornada | 21.08.2010 | Southampton | - | Leyton Orient | 1:1 | ||||
| 4. Jornada | 28.08.2010 | Bristol Rovers | - | Southampton | 0:4 | ||||
| 5. Jornada | 04.09.2010 | Southampton | - | Rochdale AFC | 0:2 | ||||
| 6. Jornada | 11.09.2010 | Swindon Town | - | Southampton | 1:0 | ||||
| 2. Jornada | 15.09.2010 | Milton Keynes Dons | - | Southampton | 2:0 | ||||
| 17. Jornada | 20.11.2010 | Southampton | - | Peterborough United | 4:1 | ||||
| 20. Jornada | 11.12.2010 | Southampton | - | Brentford FC | 0:2 | ||||
| 29. Jornada | 05.04.2011 | Southampton | - | Charlton Athletic | 2:0 | ||||
| 42. Jornada | 16.04.2011 | Southampton | - | Bristol Rovers | 1:0 | ||||
| 43. Jornada | 23.04.2011 | Brighton & Hove Albion | - | Southampton | 1:2 |  |
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| 44. Jornada | 25.04.2011 | Southampton | - | Hartlepool United | 2:0 | ||||
| 45. Jornada | 30.04.2011 | Brentford FC | - | Southampton | 0:3 | |
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| 39. Jornada | 02.05.2011 | Plymouth Argyle | - | Southampton | 1:3 | ||||
| 46. Jornada | 07.05.2011 | Southampton | - | Walsall FC | 3:1 | |
Irlanda