| 3. Jornada | 09.05.2019 | Columbus Crew | - | Los Angeles Galaxy | 3:1 | ||||
| 3. Jornada | 12.05.2019 | Columbus Crew | - | Los Angeles FC | 0:3 |  |
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| 3. Jornada | 19.05.2019 | Minnesota United FC | - | Columbus Crew | 1:0 | |
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| 3. Jornada | 26.05.2019 | Colorado Rapids | - | Columbus Crew | 3:2 | ||||
| 4. Jornada | 02.06.2019 | Columbus Crew | - | New York City FC | 2:2 | |
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| 4. Jornada | 23.06.2019 | Columbus Crew | - | Sporting Kansas City | 0:1 | ||||
| 4. Jornada | 30.06.2019 | Columbus Crew | - | Orlando City | 0:2 | ||||
| 5. Jornada | 04.07.2019 | Real Salt Lake | - | Columbus Crew | 1:0 | ||||
| 5. Jornada | 07.07.2019 | Columbus Crew | - | Seattle Sounders | 1:2 | |
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| 5. Jornada | 14.07.2019 | Orlando City | - | Columbus Crew | 1:0 | ||||
| 5. Jornada | 28.07.2019 | New York RB | - | Columbus Crew | 2:3 | |
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| 6. Jornada | 22.08.2019 | New York City FC | - | Columbus Crew | 1:0 | |
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| 7. Jornada | 01.09.2019 | Columbus Crew | - | Chicago Fire | 1:1 | ||||
| 7. Jornada | 15.09.2019 | Atlanta United FC | - | Columbus Crew | 1:3 | ||||
| 7. Jornada | 21.09.2019 | Vancouver Whitecaps | - | Columbus Crew | 1:1 | ||||
| 7. Jornada | 29.09.2019 | Columbus Crew | - | Philadelphia Union | 2:0 |
Costa Rica