| 1. Jornada | 04.02.2012 | Libertad | - | Club Nacional | 1:0 |  |
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| 4. Jornada | 25.02.2012 | Club Nacional | - | Sol de América | 2:1 | ||||
| 6. Jornada | 10.03.2012 | Club Nacional | - | Cerro Porteño | 2:0 | |
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| 11. Jornada | 16.04.2012 | Sportivo Luqueño | - | Club Nacional | 2:1 | ||||
| 13. Jornada | 23.04.2012 | Tacuary | - | Club Nacional | 0:3 | ||||
| 14. Jornada | 28.04.2012 | Club Nacional | - | Guaraní | 1:1 | ||||
| 15. Jornada | 06.05.2012 | Sol de América | - | Club Nacional | 3:2 | ||||
| 16. Jornada | 13.05.2012 | Club Nacional | - | Club Olimpia | 0:0 | |
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| 12. Jornada | 06.06.2012 | Club Nacional | - | Libertad | 1:2 | ||||
| 17. Jornada | 14.06.2012 | Cerro Porteño | - | Club Nacional | 2:1 | ||||
| 21. Jornada | 04.07.2012 | Club Rubio Ñu | - | Club Nacional | 3:3 |
Paraguay