| 2. Jornada | 16.01.2022 | Atlas Guadalajara | - | Atlético San Luis | 1:0 | ||||
| 1. Jornada | 20.01.2022 | Club León | - | Atlas Guadalajara | 1:1 | ||||
| 3. Jornada | 23.01.2022 | CF América | - | Atlas Guadalajara | 0:2 |  |
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| 4. Jornada | 07.02.2022 | Atlas Guadalajara | - | Santos Laguna | 2:1 | ||||
| 5. Jornada | 12.02.2022 | Puebla FC | - | Atlas Guadalajara | 1:1 | ||||
| 6. Jornada | 21.02.2022 | Atlas Guadalajara | - | Pumas UNAM | 0:0 |
México