| 1. Jornada | 24.07.2021 | NK Veres | - | Kolos Kovalivka | 0:0 | ||||
| 2. Jornada | 30.07.2021 | Kolos Kovalivka | - | Metalist 1925 Kharkiv | 1:0 |  |
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| 4. Jornada | 15.08.2021 | Kolos Kovalivka | - | Rukh Lviv | 1:1 | ||||
| 5. Jornada | 22.08.2021 | Kolos Kovalivka | - | FK Oleksandriya | 0:1 | |
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| 6. Jornada | 28.08.2021 | Dinamo Kiev | - | Kolos Kovalivka | 7:0 | |
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| 7. Jornada | 12.09.2021 | Kolos Kovalivka | - | FK Mariupol | 1:3 | ||||
| 11. Jornada | 16.10.2021 | SK Dnipro-1 | - | Kolos Kovalivka | 2:0 | ||||
| 13. Jornada | 31.10.2021 | Kolos Kovalivka | - | FK Lviv | 0:1 | ||||
| 15. Jornada | 21.11.2021 | Desna Chernigov | - | Kolos Kovalivka | 0:1 |  |
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| 17. Jornada | 04.12.2021 | Metalist 1925 Kharkiv | - | Kolos Kovalivka | 0:1 |  |
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| 18. Jornada | 12.12.2021 | Kolos Kovalivka | - | FC Mynai | 2:1 |
Brasil