| 18. Jornada | 08.01.2022 | Real Unión | - | Extremadura UD | 0:1 | ||||
| 19. Jornada | 22.01.2022 | Bilbao Athletic | - | Extremadura UD | 3:0 |  |
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| 20. Jornada | 27.01.2022 | Extremadura UD | - | CF Talavera | 0:2 | ||||
| 21. Jornada | 30.01.2022 | Inter de Madrid | - | Extremadura UD | 4:2 | ||||
| 22. Jornada | 04.02.2022 | Extremadura UD | - | UD SS Reyes | 0:6 | ||||
| 23. Jornada | 12.02.2022 | CD Calahorra | - | Extremadura UD | 6:1 | ||||
| 24. Jornada | 19.02.2022 | Extremadura UD | - | CyD Leonesa | 1:3 |
España