| 4. Jornada | 05.02.2022 | Club Necaxa [Sub 20] | - | CF Pachuca [Sub 20] | 1:2 | ||||
| 11. Jornada | 19.03.2022 | Pumas UNAM [Sub 20] | - | Club Necaxa [Sub 20] | 1:2 | ||||
| 1. Jornada | 25.03.2022 | FC Juárez [Sub 20] | - | Club Necaxa [Sub 20] | 3:2 | ||||
| 12. Jornada | 02.04.2022 | Club Necaxa [Sub 20] | - | CF América [Sub 20] | 1:2 | ||||
| 13. Jornada | 07.04.2022 | Atlas Guadalajara [Sub 20] | - | Club Necaxa [Sub 20] | 1:1 |  |
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| 14. Jornada | 15.04.2022 | Club Necaxa [Sub 20] | - | Atlético San Luis [Sub 20] | 3:0 | ||||
| 15. Jornada | 19.04.2022 | Club Necaxa [Sub 20] | - | UANL Tigres [Sub 20] | 0:2 | ||||
| 16. Jornada | 22.04.2022 | Puebla FC [Sub 20] | - | Club Necaxa [Sub 20] | 1:3 |
México