| 4. Jornada | 18.02.2023 | Guaireña FC | - | Cerro Porteño | 0:2 | ||||
| 9. Jornada | 24.03.2023 | Guaraní | - | Guaireña FC | 1:1 | ||||
| 10. Jornada | 02.04.2023 | Guaireña FC | - | Resistencia SC | 1:3 |  |
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| 13. Jornada | 15.04.2023 | Guaireña FC | - | Tacuary | 0:1 | ||||
| 14. Jornada | 22.04.2023 | Sportivo Trinidense | - | Guaireña FC | 1:0 |  |
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| 15. Jornada | 29.04.2023 | Cerro Porteño | - | Guaireña FC | 2:0 | ||||
| 16. Jornada | 08.05.2023 | Guaireña FC | - | Club Olimpia | 1:0 | ||||
| 17. Jornada | 12.05.2023 | General Caballero DJLM | - | Guaireña FC | 3:0 | ||||
| 18. Jornada | 17.05.2023 | Guaireña FC | - | Libertad | 0:2 | ||||
| 19. Jornada | 22.05.2023 | Sportivo Ameliano | - | Guaireña FC | 1:1 | ||||
| 20. Jornada | 29.05.2023 | Guaireña FC | - | Guaraní | 2:2 | |
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| 21. Jornada | 04.06.2023 | Resistencia SC | - | Guaireña FC | 0:2 | |
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| 22. Jornada | 09.06.2023 | Guaireña FC | - | Sportivo Luqueño | 0:2 |
Paraguay