| 7. Jornada | 19.09.2020 | MFK Ružomberok | - | MFK Zemplín Michalovce | 4:0 | ||||
| 9. Jornada | 03.10.2020 | ŠKF Sereď | - | MFK Zemplín Michalovce | 1:1 | ||||
| 12. Jornada | 31.10.2020 | Spartak Trnava | - | MFK Zemplín Michalovce | 1:2 |  |
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| 13. Jornada | 07.11.2020 | MFK Zemplín Michalovce | - | Slovan Bratislava | 0:2 | ||||
| 14. Jornada | 21.11.2020 | MFK Zemplín Michalovce | - | FK Senica | 0:1 | ||||
| 15. Jornada | 28.11.2020 | Zlaté Moravce | - | MFK Zemplín Michalovce | 0:0 | ||||
| 16. Jornada | 05.12.2020 | MFK Zemplín Michalovce | - | MŠK Žilina | 1:1 | ||||
| 19. Jornada | 14.02.2021 | FK Pohronie | - | MFK Zemplín Michalovce | 1:1 | ||||
| 21. Jornada | 27.02.2021 | FC DAC 1904 | - | MFK Zemplín Michalovce | 2:1 |
Grecia