| 1. Jornada | 17.07.2021 | Gaz Metan Mediaş | - | CS Mioveni | 1:0 | ||||
| 4. Jornada | 08.08.2021 | FCSB | - | Gaz Metan Mediaş | 2:1 | ||||
| 6. Jornada | 21.08.2021 | CS Universitatea Craiova | - | Gaz Metan Mediaş | 1:0 |  |
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| 7. Jornada | 30.08.2021 | Gaz Metan Mediaş | - | UTA Arad | 0:1 | ||||
| 8. Jornada | 12.09.2021 | Gaz Metan Mediaş | - | FC Voluntari | 1:2 | ||||
| 9. Jornada | 17.09.2021 | Rapid Bucureşti | - | Gaz Metan Mediaş | 1:2 | ||||
| 10. Jornada | 27.09.2021 | Gaz Metan Mediaş | - | Sepsi OSK | 0:0 | ||||
| 11. Jornada | 03.10.2021 | CFR Cluj | - | Gaz Metan Mediaş | 2:1 | ||||
| 15. Jornada | 05.11.2021 | Chindia Târgoviște | - | Gaz Metan Mediaş | 0:1 | |
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| 27. Jornada | 18.02.2022 | Dinamo Bucureşti | - | Gaz Metan Mediaş | 4:0 | ||||
| 28. Jornada | 26.02.2022 | Gaz Metan Mediaş | - | FC Universitatea Craiova | 0:3 | ||||
| 29. Jornada | 02.03.2022 | Academica Clinceni | - | Gaz Metan Mediaş | 2:0 | ||||
| 30. Jornada | 06.03.2022 | Gaz Metan Mediaş | - | Chindia Târgoviște | 0:4 |
Rumania