| 1. Jornada | 17.03.2018 | Minnesota United FC | - | Chicago Fire | 2:1 | ||||
| 2. Jornada | 01.04.2018 | Chicago Fire | - | Portland Timbers | 2:2 | ||||
| 2. Jornada | 08.04.2018 | Chicago Fire | - | Columbus Crew | 1:0 | ||||
| 3. Jornada | 31.05.2018 | Philadelphia Union | - | Chicago Fire | 3:1 | ||||
| 5. Jornada | 15.07.2018 | FC Dallas | - | Chicago Fire | 3:1 |  |
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| 6. Jornada | 05.08.2018 | Real Salt Lake | - | Chicago Fire | 2:1 |  |
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| 6. Jornada | 12.08.2018 | Chicago Fire | - | New York RB | 0:1 | ||||
| 6. Jornada | 19.08.2018 | Impact de Montréal | - | Chicago Fire | 2:1 | ||||
| 7. Jornada | 16.09.2018 | Chicago Fire | - | Orlando City | 4:0 | ||||
| 7. Jornada | 27.09.2018 | New York City FC | - | Chicago Fire | 2:0 | ||||
| 7. Jornada | 29.09.2018 | Chicago Fire | - | Los Angeles FC | 3:1 |
Estados Unidos