| 3. Jornada | 21.01.2022 | Sporting FC | - | Guadalupe | 2:2 | ||||
| 4. Jornada | 04.02.2022 | Guadalupe | - | AD San Carlos | 3:1 | ||||
| 14. Jornada | 17.04.2022 | Guadalupe | - | Sporting FC | 4:2 | ||||
| 16. Jornada | 24.04.2022 | Municipal Grecia | - | Guadalupe | 3:2 | ||||
| 21. Jornada | 13.05.2022 | CS Herediano | - | Guadalupe | 0:0 | ||||
| 22. Jornada | 15.05.2022 | Guadalupe | - | AD Guanacasteca | 0:0 |
Costa Rica