| 7. Jornada | 19.02.2022 | CF Pachuca [Sub 16] | - | Gallos Blancos [Sub 16] | 5:1 | ||||
| 8. Jornada | 26.02.2022 | CF Pachuca [Sub 16] | - | FC Juárez [Sub 16] | 4:2 | ||||
| 9. Jornada | 05.03.2022 | Deportivo Toluca [Sub 16] | - | CF Pachuca [Sub 16] | 1:1 | ||||
| 10. Jornada | 12.03.2022 | CF Pachuca [Sub 16] | - | Cruz Azul [Sub 16] | 2:2 | ||||
| 11. Jornada | 19.03.2022 | Puebla FC [Sub 16] | - | CF Pachuca [Sub 16] | 0:4 | ||||
| 12. Jornada | 26.03.2022 | CF Pachuca [Sub 16] | - | Pumas UNAM [Sub 16] | 0:0 |
México