| 2. Jornada | 21.01.2021 | Plaza Colonia | - | Progreso | 0:1 |  |
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| 3. Jornada | 29.01.2021 | Fénix | - | Plaza Colonia | 3:3 | |
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| 5. Jornada | 07.02.2021 | Defensor Sporting | - | Plaza Colonia | 3:2 | ||||
| 6. Jornada | 10.02.2021 | Plaza Colonia | - | Danubio | 3:0 | ||||
| 7. Jornada | 14.02.2021 | Nacional | - | Plaza Colonia | 1:1 | ||||
| 10. Jornada | 01.03.2021 | Plaza Colonia | - | Rentistas | 5:0 | ||||
| 14. Jornada | 26.03.2021 | Plaza Colonia | - | River Plate | 1:0 | ||||
| 15. Jornada | 29.03.2021 | Montevideo City Torque | - | Plaza Colonia | 2:0 |
Argentina