| 2. Jornada | 07.02.2010 | Sport Colombia | - | Sportivo Trinidense | 0:0 | ||||
| 3. Jornada | 13.02.2010 | Club Nacional | - | Sport Colombia | 1:2 | ||||
| 4. Jornada | 17.02.2010 | Sport Colombia | - | 3 de Febrero | 2:3 | ||||
| 9. Jornada | 17.03.2010 | Sport Colombia | - | Guaraní | 1:3 |  |
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| 10. Jornada | 21.03.2010 | Club Rubio Ñu | - | Sport Colombia | 2:1 |  |
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| 11. Jornada | 28.03.2010 | Sport Colombia | - | Tacuary | 0:0 | ||||
| 12. Jornada | 04.04.2010 | Sport Colombia | - | Sportivo Luqueño | 0:1 | ||||
| 16. Jornada | 25.04.2010 | Sport Colombia | - | Sol de América | 2:2 | ||||
| 21. Jornada | 23.05.2010 | Sport Colombia | - | Club Rubio Ñu | 2:4 |
Paraguay