| 3. Jornada | 17.08.2021 | Portsmouth FC | - | Shrewsbury Town | 1:0 | ||||
| 7. Jornada | 11.09.2021 | Milton Keynes Dons | - | Portsmouth FC | 1:0 | ||||
| 8. Jornada | 18.09.2021 | Portsmouth FC | - | Cambridge United | 1:2 | ||||
| 6. Jornada | 21.09.2021 | Portsmouth FC | - | Plymouth Argyle | 2:2 | ||||
| 10. Jornada | 28.09.2021 | Burton Albion | - | Portsmouth FC | 2:1 | ||||
| 11. Jornada | 02.10.2021 | Portsmouth FC | - | Sunderland | 4:0 | ||||
| 18. Jornada | 20.11.2021 | Portsmouth FC | - | AFC Wimbledon | 2:1 | ||||
| 19. Jornada | 23.11.2021 | Lincoln City | - | Portsmouth FC | 0:3 | ||||
| 20. Jornada | 27.11.2021 | Gillingham FC | - | Portsmouth FC | 0:1 | ||||
| 21. Jornada | 07.12.2021 | Portsmouth FC | - | Sheffield Wednesday | 0:0 | ||||
| 22. Jornada | 11.12.2021 | Portsmouth FC | - | Morecambe FC | 2:0 |
Gales