| 1. Jornada | 22.08.2020 | Paphos FC | - | Omonia Nikosia | 2:2 |  |
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| 2. Jornada | 30.08.2020 | Omonia Nikosia | - | Karmiotissa Polemidion | 1:0 | ||||
| 3. Jornada | 12.09.2020 | Anorthosis Famagusta | - | Omonia Nikosia | 1:1 | ||||
| 6. Jornada | 04.10.2020 | Omonia Nikosia | - | AEL Limassol | 3:0 | |
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| 7. Jornada | 18.10.2020 | Ethnikos Achna | - | Omonia Nikosia | 1:2 | |
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| 9. Jornada | 01.11.2020 | Olympiacos Nikosia | - | Omonia Nikosia | 1:0 | ||||
| 10. Jornada | 08.11.2020 | Omonia Nikosia | - | Doxa Katokopias | 0:0 | ||||
| 11. Jornada | 22.11.2020 | Nea Salamina | - | Omonia Nikosia | 2:1 | ||||
| 15. Jornada | 18.12.2020 | Karmiotissa Polemidion | - | Omonia Nikosia | 1:5 | ||||
| 16. Jornada | 22.12.2020 | Omonia Nikosia | - | Anorthosis Famagusta | 3:0 | ||||
| 17. Jornada | 03.01.2021 | AEK Larnaca | - | Omonia Nikosia | 0:3 | ||||
| 5. Jornada | 13.01.2021 | Apollon Limassol | - | Omonia Nikosia | 0:0 | ||||
| 20. Jornada | 16.01.2021 | Omonia Nikosia | - | Ethnikos Achna | 2:0 | ||||
| 21. Jornada | 23.01.2021 | Enosis Neon Paralimni | - | Omonia Nikosia | 0:1 | ||||
| 23. Jornada | 05.02.2021 | Doxa Katokopias | - | Omonia Nikosia | 0:3 | ||||
| 25. Jornada | 13.02.2021 | Ermis Aradippou | - | Omonia Nikosia | 0:2 |
Francia