| 4. Jornada | 26.02.2022 | Platense | - | Banfield | 0:1 | ||||
| 5. Jornada | 06.03.2022 | Banfield | - | Defensa y Justicia | 2:3 | ||||
| 6. Jornada | 13.03.2022 | Unión de Santa Fe | - | Banfield | 2:1 | ||||
| 7. Jornada | 19.03.2022 | CA Lanús | - | Banfield | 0:1 |  |
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| 8. Jornada | 02.04.2022 | Banfield | - | Argentinos Juniors | 0:2 | ||||
| 9. Jornada | 10.04.2022 | Patronato de Paraná | - | Banfield | 0:1 | ||||
| 10. Jornada | 18.04.2022 | Banfield | - | River Plate | 1:2 | ||||
| 11. Jornada | 20.04.2022 | Newell's Old Boys | - | Banfield | 1:0 | ||||
| 13. Jornada | 30.04.2022 | Racing Club | - | Banfield | 1:1 |
Paraguay