| 4. Jornada | 07.02.2016 | Club Rubio Ñu | - | General Díaz | 0:0 | ||||
| 5. Jornada | 13.02.2016 | Cerro Porteño | - | Club Rubio Ñu | 1:2 |  |
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| 6. Jornada | 19.02.2016 | Club Rubio Ñu | - | Sportivo Luqueño | 1:2 | ||||
| 7. Jornada | 27.02.2016 | General Caballero ZC | - | Club Rubio Ñu | 0:1 |  |
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| 8. Jornada | 01.03.2016 | Club Rubio Ñu | - | Guaraní | 2:2 | |
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| 9. Jornada | 05.03.2016 | River Plate | - | Club Rubio Ñu | 1:4 | |
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| 10. Jornada | 13.03.2016 | Club Olimpia | - | Club Rubio Ñu | 4:1 |  |
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| 12. Jornada | 04.04.2016 | Club Rubio Ñu | - | Libertad | 2:0 | ||||
| 13. Jornada | 07.04.2016 | Club Nacional | - | Club Rubio Ñu | 3:1 | ||||
| 15. Jornada | 15.04.2016 | General Díaz | - | Club Rubio Ñu | 0:2 | ||||
| 18. Jornada | 30.04.2016 | Club Rubio Ñu | - | General Caballero ZC | 1:2 | |
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| 19. Jornada | 05.05.2016 | Guaraní | - | Club Rubio Ñu | 3:1 | |
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| 20. Jornada | 08.05.2016 | Club Rubio Ñu | - | River Plate | 1:2 | |
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| 16. Jornada | 12.05.2016 | Club Rubio Ñu | - | Cerro Porteño | 1:0 | |
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| 21. Jornada | 15.05.2016 | Club Rubio Ñu | - | Club Olimpia | 1:4 | |
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| 22. Jornada | 20.05.2016 | Sol de América | - | Club Rubio Ñu | 1:2 | |
Paraguay