| 1. Jornada | 03.06.2021 | Atenas | - | Rampla Juniors | 1:1 | ||||
| 2. Jornada | 10.06.2021 | Rampla Juniors | - | Racing | 2:2 | ||||
| 6. Jornada | 08.07.2021 | Rampla Juniors | - | Albion | 0:1 | ||||
| 7. Jornada | 16.07.2021 | Rampla Juniors | - | Danubio | 0:0 | ||||
| 9. Jornada | 31.07.2021 | Rampla Juniors | - | CA Cerro | 0:1 | ||||
| 10. Jornada | 05.08.2021 | Defensor Sporting | - | Rampla Juniors | 1:0 | ||||
| 17. Jornada | 19.10.2021 | Albion | - | Rampla Juniors | 2:0 |  |
|||
| 21. Jornada | 18.11.2021 | Rampla Juniors | - | Defensor Sporting | 0:5 |
Uruguay