| 1. Jornada | 30.01.2023 | Club Olimpia | - | Sportivo Luqueño | 2:1 |  |
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| 3. Jornada | 13.02.2023 | Club Olimpia | - | Tacuary | 4:0 | |
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| 4. Jornada | 18.02.2023 | Sportivo Trinidense | - | Club Olimpia | 3:1 | ||||
| 5. Jornada | 27.02.2023 | Club Olimpia | - | Guaireña FC | 1:1 | ||||
| 6. Jornada | 04.03.2023 | Club Olimpia | - | Cerro Porteño | 2:2 |  |
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| 2. Jornada | 08.03.2023 | Club Nacional | - | Club Olimpia | 1:1 | ||||
| 8. Jornada | 19.03.2023 | Club Olimpia | - | Libertad | 2:1 | |
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| 9. Jornada | 25.03.2023 | Sportivo Ameliano | - | Club Olimpia | 2:2 | ||||
| 11. Jornada | 09.04.2023 | Resistencia SC | - | Club Olimpia | 0:3 | |
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| 13. Jornada | 16.04.2023 | Club Olimpia | - | Club Nacional | 0:1 | ||||
| 14. Jornada | 24.04.2023 | Tacuary | - | Club Olimpia | 0:1 | ||||
| 16. Jornada | 08.05.2023 | Guaireña FC | - | Club Olimpia | 1:0 | ||||
| 17. Jornada | 13.05.2023 | Cerro Porteño | - | Club Olimpia | 2:2 | |
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| 18. Jornada | 17.05.2023 | Club Olimpia | - | General Caballero DJLM | 1:1 | |
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| 19. Jornada | 21.05.2023 | Libertad | - | Club Olimpia | 1:0 | ||||
| 20. Jornada | 30.05.2023 | Club Olimpia | - | Sportivo Ameliano | 1:3 | ||||
| 22. Jornada | 12.06.2023 | Club Olimpia | - | Resistencia SC | 4:1 |
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