| 5. Jornada | 03.10.2021 | Olympiacos | - | Panathinaikos | 0:0 | ||||
| 6. Jornada | 16.10.2021 | Panathinaikos | - | Ionikos Nikea | 4:1 | ||||
| 7. Jornada | 23.10.2021 | Asteras Tripolis | - | Panathinaikos | 2:1 | ||||
| 13. Jornada | 11.12.2021 | Panathinaikos | - | Atromitos | 2:0 | ||||
| 15. Jornada | 19.12.2021 | Panathinaikos | - | PAS Giannina | 2:0 |  |
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| 16. Jornada | 05.01.2022 | Panathinaikos | - | Aris Saloniki | 2:0 | ||||
| 17. Jornada | 09.01.2022 | Volos NFC | - | Panathinaikos | 3:1 |  |
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| 20. Jornada | 29.01.2022 | Panathinaikos | - | Asteras Tripolis | 0:1 | ||||
| 21. Jornada | 02.02.2022 | OFI Heraklion | - | Panathinaikos | 3:2 | ||||
| 22. Jornada | 06.02.2022 | PAOK Saloniki | - | Panathinaikos | 2:1 | ||||
| 23. Jornada | 13.02.2022 | Panathinaikos | - | Lamia | 2:0 | ||||
| 14. Jornada | 16.02.2022 | Apollon Smyrnis | - | Panathinaikos | 0:3 | ||||
| 24. Jornada | 19.02.2022 | Panetolikos | - | Panathinaikos | 1:0 | ||||
| 25. Jornada | 27.02.2022 | Panathinaikos | - | AEK Athen | 3:0 | ||||
| 26. Jornada | 06.03.2022 | Atromitos | - | Panathinaikos | 0:2 |
Argentina
