| 1. Jornada | 23.08.2021 | Apollon Limassol | - | Ethnikos Achna | 4:2 | ||||
| 2. Jornada | 11.09.2021 | Aris Limassol | - | Apollon Limassol | 0:1 | ||||
| 3. Jornada | 19.09.2021 | Apollon Limassol | - | APOEL Nikosia | 2:1 | ||||
| 4. Jornada | 26.09.2021 | AEL Limassol | - | Apollon Limassol | 0:1 |  |
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| 7. Jornada | 23.10.2021 | Apollon Limassol | - | Paphos FC | 2:0 | |
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| 8. Jornada | 31.10.2021 | Olympiacos Nikosia | - | Apollon Limassol | 0:2 | ||||
| 10. Jornada | 22.11.2021 | Apollon Limassol | - | PAEEK | 3:1 | |
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| 11. Jornada | 29.11.2021 | Anorthosis Famagusta | - | Apollon Limassol | 1:1 | ||||
| 14. Jornada | 18.12.2021 | APOEL Nikosia | - | Apollon Limassol | 1:1 | ||||
| 16. Jornada | 08.01.2022 | AEK Larnaca | - | Apollon Limassol | 2:1 | |
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| 22. Jornada | 26.02.2022 | Apollon Limassol | - | Anorthosis Famagusta | 2:2 |
Chipre
Congo