| 1. Jornada | 07.08.2021 | RFCU Luxemburg | - | Swift Hesperange | 0:3 |  |
|||
| 2. Jornada | 14.08.2021 | FC Rodange 91 | - | RFCU Luxemburg | 0:1 | ||||
| 3. Jornada | 21.08.2021 | RFCU Luxemburg | - | RM Hamm Benfica | 1:0 | |
|||
| 4. Jornada | 28.08.2021 | FC Wiltz 71 | - | RFCU Luxemburg | 2:3 | ||||
| 6. Jornada | 18.09.2021 | Jeunesse Esch | - | RFCU Luxemburg | 0:2 | ||||
| 7. Jornada | 22.09.2021 | RFCU Luxemburg | - | US Hostert | 7:0 | ||||
| 8. Jornada | 26.09.2021 | Progrès Niedercorn | - | RFCU Luxemburg | 0:2 | |
|||
| 10. Jornada | 23.10.2021 | RFCU Luxemburg | - | US Mondorf | 2:1 | ||||
| 12. Jornada | 21.11.2021 | RFCU Luxemburg | - | FC Differdange 03 | 3:1 | ||||
| 13. Jornada | 28.11.2021 | Victoria Rosport | - | RFCU Luxemburg | 3:1 | |
|||
| 14. Jornada | 04.12.2021 | RFCU Luxemburg | - | CS FOLA Esch | 0:1 | ||||
| 15. Jornada | 11.12.2021 | UNA Strassen | - | RFCU Luxemburg | 3:0 |
Luxemburgo
Argelia