| 20. Jornada | 05.02.2022 | Atlético Levante | - | CS Puertollano CF | 0:0 | ||||
| 21. Jornada | 13.02.2022 | CS Puertollano CF | - | CD Toledo | 2:1 | ||||
| 22. Jornada | 20.02.2022 | CD El Ejido 2012 | - | CS Puertollano CF | 2:0 | ||||
| 23. Jornada | 27.02.2022 | CS Puertollano CF | - | CD Marchamalo | 1:2 | ||||
| 24. Jornada | 06.03.2022 | CF La Nucía | - | CS Puertollano CF | 3:2 |  |
|||
| 25. Jornada | 13.03.2022 | CS Puertollano CF | - | Granada B | 3:0 |  |
|||
| 26. Jornada | 20.03.2022 | CD Eldense | - | CS Puertollano CF | 3:2 | ||||
| 27. Jornada | 27.03.2022 | CS Puertollano CF | - | CF Intercity | 0:1 | ||||
| 28. Jornada | 03.04.2022 | Hércules CF | - | CS Puertollano CF | 2:1 | |
|||
| 29. Jornada | 10.04.2022 | CS Puertollano CF | - | Mar Menor CF | 4:0 | |
|
||
| 30. Jornada | 17.04.2022 | Real Murcia | - | CS Puertollano CF | 3:1 | |
|||
| 31. Jornada | 24.04.2022 | CS Puertollano CF | - | UD Alzira | 1:3 | |
Uruguay
España