| 2. Jornada | 10.06.2021 | Uruguay Montevideo | - | Villa Teresa | 2:3 | ||||
| 4. Jornada | 25.06.2021 | Uruguay Montevideo | - | Albion | 2:2 | ||||
| 5. Jornada | 02.07.2021 | Uruguay Montevideo | - | Rampla Juniors | 2:0 | ||||
| 6. Jornada | 08.07.2021 | Danubio | - | Uruguay Montevideo | 1:0 | ||||
| 9. Jornada | 28.07.2021 | Uruguay Montevideo | - | Defensor Sporting | 0:2 |  |
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| 11. Jornada | 12.08.2021 | Uruguay Montevideo | - | Atenas | 0:0 | ||||
| 16. Jornada | 13.10.2021 | Rampla Juniors | - | Uruguay Montevideo | 1:1 | ||||
| 22. Jornada | 23.11.2021 | Atenas | - | Uruguay Montevideo | 0:0 |
Uruguay