| 1. Jornada | 20.01.2008 | CF América | - | Puebla FC | 0:0 | ||||
| 2. Jornada | 27.01.2008 | Puebla FC | - | CF Monterrey | 1:1 |  |
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| 3. Jornada | 03.02.2008 | Puebla FC | - | Club Necaxa | 1:1 | ||||
| 4. Jornada | 10.02.2008 | Jaguares Chiapas | - | Puebla FC | 0:1 | |
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| 5. Jornada | 14.02.2008 | Puebla FC | - | Pumas UNAM | 1:1 | ||||
| 6. Jornada | 17.02.2008 | UAG Tecos | - | Puebla FC | 3:2 | ||||
| 8. Jornada | 02.03.2008 | Atlas Guadalajara | - | Puebla FC | 2:1 | ||||
| 10. Jornada | 16.03.2008 | UANL Tigres | - | Puebla FC | 0:3 | ||||
| 12. Jornada | 30.03.2008 | Cruz Azul | - | Puebla FC | 2:0 | ||||
| 13. Jornada | 06.04.2008 | Puebla FC | - | Deportivo Toluca | 1:2 | ||||
| 14. Jornada | 12.04.2008 | Veracruz (old) | - | Puebla FC | 0:2 | ||||
| 15. Jornada | 20.04.2008 | Puebla FC | - | CF Pachuca | 5:2 | ||||
| 16. Jornada | 27.04.2008 | Deportivo Guadalajara | - | Puebla FC | 4:0 | |
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| 17. Jornada | 04.05.2008 | Puebla FC | - | Atlante | 2:2 |
México